8Coldstein J Burgers.Chips,genes,great issues for medicine in the twenty-frrst century[J].Annals New York Academy of Sciences,1999,1882:9-21.
9muller R H,Keck C M.Challenges and solutions for the delivery of biotech drugs-a review of drug nanocrystal technology and lipid nanopartical[J].Biotechnology,2004,113:151-170.
10Johnson I S.The trials and tribulations of producing the first genetically engineeredgrug[J].Nature Reviewa Drug Discovery,2003(2):747-751.