影响无创正压机械通气治疗急性重症胰腺炎有效性的因素分析被引量：1

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摘要目的分析无创正压机械通气(NIPPV)治疗急性重症胰腺炎患者的临床转归,探讨影响NIPPV治疗急性重症胰腺炎有效性的因素。方法采用回顾性分析的方法,将2004年1月～2009年12月收入综合ICU并接受NIPPV治疗的急性重症胰腺炎患者,根据NIPPV治疗是否有效,将患者分为有效组和无效组进行对照研究。结果共有40例患者进入该研究。其中有效组24例,无效组16例。入院时两组患者除血浆白蛋白水平外,其他临床资料及Ranson评分的差异均无统计学意义。导致患者急性呼吸衰竭的诱因以急性肺损伤为主(60%),在无效组中则主要为肺部感染(76.4%)。患者入院时的血气分析显示两组患者动脉血氧分压均明显低于正常(63.0l±8.03 mmHg,61.21±10.74 mmHg,P>0.05),且无明显差异。经lhNIPPV治疗后,有效组患者动脉血氧分压明显提高。无效组则改善不明显,两者具有明显统计学差异(99.9±30.1mmHg,63.8±11.9mmHg.P<0.05)。结论影响NIPPV治疗急性重症胰腺炎患者急性呼吸衰竭有效性的因素,与患者的血浆白蛋白水平和发生急性呼吸衰竭的诱发因素相关,以急性肺损伤为诱发因素者,更适于接受NIPPV治疗;动脉血氧分压能预测NIPPV治疗急性重症胰腺炎患者的有效性。

作者吴金保

机构地区江西省进贤县人民医院内

出处《江西医药》 CAS 2010年第12期1201-1203,共3页 Jiangxi Medical Journal

关键词无创正压机械通气急性重症胰腺炎急性呼吸衰竭

分类号 R576 [医药卫生—消化系统]

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