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利用生物信息学解码小鼠抗凋亡基因Hax-1及其蛋白的结构与特性

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摘要 目的:分析预测小鼠抗凋亡基因HS1-associated protein X-1(Hax-1)及其蛋白的结构与特性,用于指导对其生物学功能和应用的实验研究。方法:利用生物信息网站和蛋白分析系统并结合生物信息学分析软件包,分析Hax-1基因的结构及其编码的蛋白质的理化特性、功能域等。结果:该基因全长1117bp,与GenBank中其它物种的完整的Hax-1序列相比,为全长基因。GenBank中同源性最高的序列是人的序列,二者具有非常相似的拓扑结构和空间构象。结论:Hax-1可能是筛选药物的靶标分子,具有进一步研究的价值。
机构地区 长沙医学院
出处 《内蒙古中医药》 2010年第24期49-49,共1页 Inner Mongolia Journal of Traditional Chinese Medicine
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