单鼻孔-蝶窦入路显微切除垂体腺瘤

Monorhinic transsphenoidal surgery for microsurgical removal of pituitary adenomas

目的探讨单鼻孔-蝶窦入路显微切除垂体腺瘤的临床意义。方法回顾性分析鼻-蝶窦显微入路切除垂体腺瘤50例的治疗效果。结果肿瘤全切除35例,次全切除11例,大部分切除4例。术后脑脊液漏5例,尿崩症12例,术后临床症状均有不同程度改善,无死亡病例。结论鼻-蝶窦入路显微切除垂体腺瘤具有创伤小、风险低、术后并发症少、费用低等特点,是目前垂体腺瘤切除术的首选治疗方法。

Objective To explore the clinical significance of treatment of pituitary adenoma by transsphenoidal approach through unilateral nasal cavity.Methods The treating effects of 50 cases with nasal-transsphenoidal microsurgery for pituitary adenoma were analysied retrospectively.Results Of the patients,35 cases were conducted total resection,11 cases subtotal resection,4 cases partial resection.No postoperative death,5 cases had cerebrospinal fluid leakage,12 cases diabetes insipid,clinical symptoms were improved with different degrees.Conclusion Nasal-transsphenoidal microsurgical resection of pituitary adenoma has the functions of less trauma and low-risk,less postoperative complications,lower cost and it is the first choice for resection of pituitary tumor treatment.