期刊文献+

头孢地嗪治疗高龄急腹症患者术后继发肺部感染的疗效及对免疫功能影响 被引量:1

下载PDF
导出
摘要 目的观察头孢地嗪和头孢曲松治疗高龄急腹症患者术后继发肺部感染的疗效及对免疫功能的影响。方法97例患者随机分为两组,分别使用头孢地嗪和头孢曲松,疗程10~14d,观察两种药物治疗肺部感染的临床疗效、对T淋巴细胞亚群的影响。结果头孢地嗪组48例患者,细菌清除率85.71%,临床有效率83.33%,CD4(49.90±12.25)%,CD4/CD8(1.29±0.38)%,头孢曲松组49例患者,细菌清除率70.37%,临床有效率71.43%,CD4(40.71±13.04)%,CD4/CD8(1.05±0.49)%。两组比较差异有统计学意义(P〈0.05)。结论头孢地嗪对高龄急腹症患者术后继发肺部感染有较好的疗效,且具有提高免疫作用。
出处 《临床外科杂志》 2010年第7期490-492,共3页 Journal of Clinical Surgery
  • 相关文献

参考文献8

  • 1Van VB,Vanholder R,De Paepe P,et al.Immunomodulatingefecte of antibiotics:literature review[J].Infection,1996,24 (4):275 -291.
  • 2Blandino G,Milazzo I,Musumeci R,et al.Comparative activity of cefodizime and ceftriaxone against respiratory pathogens in an invitro pharmacod ynamic model simulating concentration-time curves[J].J Chemother,2000,12(6):503-508.
  • 3Braga PC,Sasso MD,Sala MT.Sub-MIC concentrations of cefodizime interfere with various factors afecting bacterial virulence[J].J Antimicrob Chemother,2000,45 (1):15 -25.
  • 4Hamilton-Miller JM.Immunopharrnacology of antibiotics:direct and indirect immunomodulation of defence mechanisms[J].J Chemother,2001,13(2):107-111.
  • 5Braga PC,Dal Sasso M,Mancini L,et al.Influence of subminimum inhibitory concentrations of cefodizime on the phagocytosis,intracelular Idling an doxidative bursts of human polymorphonuclear leukocytes[J].Chemotherapy,1999,45(3):166-174.
  • 6Guerra-Infante FM,Zamora-Ruiz A,L(O)pez-Hurtado M,et al.Induction of tumor necrosis factor-alpha by cefodizime in U-937 cells[J].Rev Invest Clin,2001,53(4):335-339.
  • 7Song H,Li G,Ye J,et al.Immunomodulating effects of cefodizime on Klebsiella pneumoniae-stimulated neutrophils[J].Immunobiology,2004,209(3):277-282.
  • 8Mazzei T,Novelli A,Esposito S,et al.Cefodizime in skin suction blister fluid and serum following a single intravenous or intramuscular dose in adult patients[J].J Chemother,2000,12(4):306-313.

同被引文献7

引证文献1

二级引证文献4

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部