循征医学在新生儿重症监护病房感染控制中的应用

Application of evidence-based medicine in the infection control in neonatal intensive care unit

目的 应用循征医学的方法建立新生儿重症监护病房（NICU）感染控制流程.方法 通过对NICU感染控制相关资料的调查,确定存在的问题,利用医学文献数据库（Medline）等相关医学网站检索相关文献,进行评价整合证据,以系统科学的方法建立NICU感染控制流程.结果 对照组和观察组对比：奶瓶奶嘴清洁消毒合格率,空气、物体表面、保温箱湿化水监测以及两组医护人员洗手依从性,各项监测指标差异均具有统计学意义（P＜0.05或P＜0.01）.结论 应用循征医学的方法建立NICU感染控制流程,是科学、有效的方法.

Objective To establish infection management process by applying evidence-based medicine in neonatal intensive care unit （NICU）. Methods To find out the problems about infection management in NICU by investigating correlative materials, collect and evaluate the literatures searched by medical databases （Medline） and related web site, establish the infection management process of NICU scientifically and systematically. Results To compare control group and observation group, difference of eligible rate of disinfectant of feeding bottle nipple, air, surface, incubator humidifier water monitoring and hand washing compliance in two groups were statistically significant （P 〈 0. 05 or P 〈 0. 01）. Conclusions NICU infection management process based on scientific evidence-based medicine is a scientific and effective method.