左氧氟沙辛、坦索罗辛、曲唑酮联合治疗Ⅲ型前列腺炎118例分析

Effect of Levofloxacin combined with tamsulosin and trazodone medication in treatment of chronic bacterial（Ⅲ）prostatitis（a 118cases）analycis

目的 探讨左氧氟沙星联合坦索罗辛及曲唑酮治疗慢性非细菌性（Ⅲ型）前列腺炎的疗效. 方法 对118例慢性非细菌性前列腺炎患者采用左氧氟沙星0.2 2次/d＋坦索罗辛0.2μg每晚一次＋曲唑酮50μg3次/d,口服治疗,疗程4～12周.应用美国国立卫生研究院（NIH）慢性前列腺炎症状评分（NIH-CPSI）标准对治疗前后总评分及所包括的患者疼痛评分、排尿症状评分、生活质量评分并进行统计学分析. 结果 多数患者症状有明显改善,全部患者治疗前后NIH-CPSI总评分分别为（26.81±3.69）分、（13.41±5.31）分比较,差异有统计学意义（P＜0.01）;疼痛不适前后评分分别为（12.81±2.52）分、（8.91±3.51）分比较,差异有统计学意义（P＜0.01）;排尿症状前后评分分别为（5.76±1.89）分、（2.79±1.38）分（P＜0.01）;生活质量前后评分分别为（9.12±3.21）分、（4.28±2.46）分（P＜0.01）. 结论 左氧氟沙星联合坦索罗辛及曲唑酮治疗慢性非细菌性（Ⅲ型）前列腺炎效果明显.

Objective To elxplore the effect of combined with tamsulosin and trazodone medication in treatment of chronic bacterial prostatitis（CAP,type Ⅲ）. Methods 118 cases of CAP were treated with oral levofioxacin ＋ tamsulosin ＋ trazodone for 4 ～ 12 weeks.Statistical analysis was conducted for total scores（including pain score,urinary symptom score and life quality score）according to NIH-CPSI. Results The symptoms were improved in most cases.Before and after treatment,the total scores were of all cases（26.81 ± 3.69）VS（13.41 ± 5.31）,the pain score was（12.81 ±2.52）VS（8.91 ±3.51）,the urinary symptom score was（5.76 ± 1.89）VS（2.79 ± 1.38）,and the life quality score was（9.12 ±3.21）VS（4.28 ±2.46）.There was statistically significant difference between them （all P〈0.01）. Conclusion Levofloxacin combined with tamsulosin and trazodone medication in treatment of CAP could produce obvious effects.