依达拉奉联合奥扎格雷治疗缺血性卒中30例临床研究

Clinical study of the effects of edaravone and Ozagrel in the treatment of 30 patients with acute ischemic stroke

目的 观察依达拉奉联合奥扎格雷治疗急性缺血性卒中的临床疗效及安全性. 方法 将60例急性缺血性卒中患者随机分成治疗组和对照组,治疗组30例在常规治疗基础上加用依达拉奉联合奥扎格雷,对照组30例常规治疗.两组分别于治疗前及治疗后第14d评定神经缺损评分和疗效. 结果 治疗组总有效率为86.6%,对照组总有效率为63.3%,两组差异有统计学意义（P＜0.05）. 结论 依达拉奉联合奥扎格雷治疗缺血性卒中的疗效肯定,值得进一步的研究和推广.

Objective To explore the clinical effects and safety of edaravone and ozagrel in treatment of acute ischemic stroke. Methods 60 patients with a cute ischemic stroke were divided into two groups randomly,each group 30 patients.The treatment group was treated by edaravone and ozagrel,and the control group was treated by ligustrazine injection.Before and 14 days after treatment,the neurologic impairment and clinical curative effect of the two groups were evaluated respectively. Results The effective rate in the treatment group was 86.6%,and that in the control group was 63.3%.The difference between the two groups was statistically significant（P〈0.05）. Conclusion Edaravone and ozagrel in the treatment of acute ischemic stroke was effective and worthy of being widely used.