不稳定型心绞痛患者冠脉血管内斑块的超声影像特征

Intravascular Ultrasonic Features of Unstable Atherosclerotic Plaques in Unstable Angina patients

目的 观察不稳定型心绞痛（UA）患者冠状血管内超声（IVUS）的影像学特征. 方法 对明确诊断的24例稳定型心绞痛（SA）和33例不稳定型心绞痛（UA）患者行冠状动脉造影（CAG）检查,再对犯罪血管行IVUS检查,观察病变部位的斑块特性、血栓形成、重构（正性、负性）面积. 结果 UA患者病变血管面积、斑块面积及血管重构指数明显大于SA患者（P＜0.05）,软斑块、正性重构更多见于UA患者（P＜0.05）. 结论 UA患者和SA患者冠状动脉斑块成分和结构存在显著差异,UA患者冠状动脉病变中软斑块、斑块破裂、血栓形成和正性重构更常见.

Objective To investigate the characteristics of plaque morphology of the patients with unstable angina（UA）by intravascular ultrasound（IVUS）. Methods 24 patients with stable angina pectoris（SA）and 33 patients with unstable angina（UA）were examined by coronary coronary arteriograph（CAG）and intravascular ultrasound（IVUS）.The culprit lesions about the characteristic of the plaque were studied,the external elastic membrane cross-sectional area and lumen cross-sectional area were measured,the plaque area,plaque burden,eccentricity index were calculated,and the remodeling index was examined. Results External elastic membrane area,plaque area and vascular remodeling ratio were significantly greater at target lesions in UA patients than in patients with SA（P〈0.05）.Positive remodeling and soft plaque were predominantly in UA patients（P〈0.05）. Conclusion The morphological features of coronary artery plaques in UA group were significantly different from those in SA group.More soft plaque,plaque rupture,thrombus formation,and positive remodeling were found in UA patients compared with SA patients.