近15年间急性心肌梗死患者的性别年龄演变趋势

Gender and Age Difference in Trends of Acute Myocardial Infarction Events in Recent 15 Years

目的：了解阜外心血管病医院1994年~2008年急性心肌梗死患者性别和年龄演变趋势。方法：回顾1994年~2008年出院诊断为急性心肌梗死的病历,根据时间段、首发和再发病例以及性别分别计算发病平均年龄、高峰发病年龄段和女性患者的比例,并进行统计学分析。结果：1994年至2008年期间,共收住11 859例,首发病例9 737例,再发病例2 122例。每年收治病例数呈上升趋势（P〈0.001）,差异有统计学意义。首发和再发病例中女性患者比例分别为22.0%和20.5%。女性患者比例随时间增加未见显著变化。首发病例中男性平均年龄随年度增加总体呈下降趋势（P〈0.01）,差异有统计学意义。首发病例中女性平均年龄随年度增加未见显著变化。再发病例中男性平均年龄随年度增加总体呈下降趋势（P〈0.05）,差异有统计学意义。再发病例中女性平均年龄随年度增加总体呈上升趋势（P〈0.05）,差异有统计学意义。首发病例中男性高峰发病年龄段2000年~2008年稳定在45~54岁;女性患者高峰发病年龄段1997年~2008年稳定在65~74岁。结论：急性心肌梗死男性患者发病有年轻化趋势,发病患者中女性的比例保持稳定。男性和女性患者高峰发病年龄段基本保持稳定。

Objectives：To analyze the gender and age difference in trends of acute myocardial infarction（AMI） events in recent 15 years.Methods：We retrospectively reviewed the medical records of 11 859 patients with the discharge diagnosis of acute myocardial infarction（AMI）from 1994 to 2008 in our hospital,and statistically analyzed the mean age of AMI,the peak of onset age and the proportion of female gender according to the time period,first and recurrent events of AMI.Results：There were 9737 patients with the first AMI attack and 2122 with recurrent AMI.The number of patients were increa-sing each year（P0.001）.For the first and recurrent AMI events,female were 22.0% and 20.5% respectively while the proportion of female patient was similar during 15 years of time.For the fist AMI attack,the mean age of male patients had the decreasing trend each year（P0.01）,while the mean age of female patients had no significant changes over the years.In recurrent AMI,the mean age of male patients showed a decreasing linear trend over 15 years（P0.05）,while the mean age of female patients indicated an increasing linear trend over 15 years（P0.05）.The peak of the first AMI onset age in male patients was stable between 45~54 years from 2000 to 2008,while in female patients was stablle between 65~74 years from 1997 to 2008.Conclusion：The age of AMI events in male patients was getting younger,and the proportion of female patients was stable in recent 15 years.The peak of the first onset age in both male and female patients was stable basically.