摘要
目的通过对老年男性外周血白细胞(WBC)计数与血清总胆固醇(TC)、甘油三酯(TG)含量的比较,探讨WBC水平与血脂的关系。方法从重庆市40 047例体检人群中筛选出3 740例60岁以上老年男性,根据体检结果分为高脂组(2 116例)和对照组(1 624例)。高脂组又依据血脂增高的种类再分为3个亚组,即单纯高胆固醇亚组(HTC组),784例;单纯高甘油三酯亚组(HTG组),644例;高甘油三酯合并高胆固醇组(HTC-HTG组)688例。测定各组人群外周血WBC和空腹血TC、TG含量,并进行统计学分析。结果 HTG、HTC-HTG两亚组人群WBC计数均明显高于对照组,差异有统计学意义(P<0.01);相关性分析结果显示WBC计数与TG呈正相关,差异有统计学意义(P<0.05)。结论重庆市老年男性血脂异常人群WBC计数较正常人群明显升高,外周血WBC数量与血脂异常关系密切,WBC计数可作为血脂异常的临床辅助监控指标。
Objective By comparing the peripheral blood WBC count and serum total cholesterol(TC),triglyceride(TG) concentrations of Chongqing male population over the age of 60,to explore the relationship between the level of WBC and blood lipids.Methods 3 740 cases of 60 years elderly male were collected from 40 047 cases.Samples were divided into hyperlipoidemia(2 116 cases) and control groups(1 624 cases) according to examination results.Hyperlipoidemia group was divided into high cholesterol(HTC,784 cases),high triglyceride(HTG,644 cases),high cholesterol combined with high triglycerides subgroups(HTC-HTG,688 cases).The parameters in each group were determined and analyzed by statistics.Results The WBC count was significantly higher in hyperlipoidemia group than that in control group(P0.01).The WBC counts were significantly higher in HTG and HTC-HTG subgroups than that of control group(P0.01).There was positive correlation between the WBC count and the level of TG(P0.05).Conclusions The WBC count of the elderly men with dyslipidemia is significantly higher than that of normal population,the dyslipidemia is closely related with WBC count,and WBC count can be as assisted monitor index for dyslipidemia.
出处
《中国老年学杂志》
CAS
CSCD
北大核心
2011年第3期380-382,共3页
Chinese Journal of Gerontology
基金
重庆市科委自然科学基金资助项目(CSTC,2008CE9142)
重庆医科大学创新基金资助项目(CX200528)