红药中一个新的β-萘甲酸双糖苷类化合物(英文)

A new β-naphthalenecarboxylic acid biglycoside from Chirita longgangensis var. hongyao

为了研究红药(Chirita longgangensis var.hongyao)茎的化学成分,运用多种色谱方法进行分离纯化,从其甲醇提取物中分离得到3个化合物,并根据理化性质和波谱数据鉴定其结构分别为1,4-dihydroxy-2-naphthalenecarboxylic acid methyl ester-4-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside(1),isotaxiresinol 4-O-methyl ether(2)和(R)-7-hydroxy-α-dunnione(3)。其中,化合物1为新的β-萘甲酸双糖苷化合物,化合物2为首次从该属植物中分离得到,且首次提供了化合物2的核磁波谱数据,化合物3为首次从该植物中分离得到。

To investigate the chemical constituents in the stems of Chirita longgangensis var.hongyao,methanol extract of the stems was subjected to column chromatography with various chromatographic techniques.One new β-naphthalenecarboxylic acid biglycoside,1,4-dihydroxy-2-naphthalene carboxylic acid methyl ester-4-O-α-L-rhamnopyranosyl-（1→6）-β-D-glucopyranoside（1） was isolated,along with two known compounds：isotaxiresinol 4-O-methyl ether（2） and（R）-7-hydroxy-α-dunnione（3）.Compound 2 was first obtained from Chirita genus and compound 3 was isolated from this plant for the first time.All structures were elucidated on the basis of spectral and chemical evidence,and the NMR spectroscopic data of compound 2 was published for the first time.