氟康唑和制霉菌素及凯尼汀治疗复发性外阴阴道假丝酵母菌病临床观察

Clinical Study of Fluconazole Mycostatin Combined Canesten to Treat Recurrent Vulvovaginal Candidiasis

目的比较氟康唑、制霉菌素治疗与氟康唑、制霉菌素加凯尼汀治疗复发性外阴阴道假丝酵母菌病的临床疗效。方法 60例复发性外阴阴道假丝酵母菌病患者,随机分为两组,每组各30例。A组采用氟康唑、制霉菌素治疗,B组采用氟康唑、制霉菌素加凯尼汀治疗。结果经6个疗程治疗后,两组患者大部分患者治愈,总有效率A组为88.3%,B组为96.7%,组间比较差异有显著意义(P<0.05)。结论氟康唑、制霉菌素加凯尼汀三药联合治疗复发性外阴阴道假丝酵母菌病的效果优于氟康唑、制霉菌素两药联合,且复发率低,远期效果好,值得临床推广。

Objective To study the effects of fluconazole mycostatin combined canesten to treat recurrent vulvovaginal eandidiasis. Methods Sixty cases of recurrent vulvovaginal candidiasis patients were randomly divided into two groups, each group 30 cases. Group A were treated with flueonazole and mycostatin. Croup B were treated with fluconazole myeostatin and eanesten. Results After six courses of therapy, the majority of patients were cured in two groups. The total effective rate is 88. 3% in group A and 96.7% in group B. The difference between the two groups was significant （ P 〈 0.05 ）. Conclusion Fluconazole rent vulvovaginal candidiasis patients is better than mycostatin combined canesten treatment of recurfluconazole mycostatin two -drug combination.