河南省2009年急性弛缓性麻痹病原流行病学分析

Analysis on Pathogenic Epidemiology of AFP Cases in Henan Province in 2009

目的了解河南省2009年急性弛缓性麻痹病例的监测情况。方法采集532例AFP病例标本,进行病原流行病学分析。结果分离到PV15株,阳性率为2.82%,其中PVⅡ型占所有分离PV的40%;分离到NPEV118株,阳性率为22.2%;口服脊灰减毒活疫苗＂零＂剂次免疫的AFP病例的PV分离率依次高于12次和≥3次免疫者;79例60d后随访残留麻痹的病例PVⅡ分离率为7.59%。结论 AFP病例实验室监测系统是敏感的,做好OPV常规免疫和强化免疫同样重要,PVⅡ对部分未完成全程免疫的AFP病例是一种潜在的致麻痹病因。

Objective To understand the monitor of AFP cases in 2009 in Henan.Methods Totally 532 samples were collected from AFP cases and were analyzed on the pathogenic epidemiology.Results Totally 15 strains of polio virus（PV） were isolated and the isolation rate was 2.82%,the rate of PVⅡ among all of PV was 40%;118 strains of non-poliomyelitis enterovirus（NPEV） were isolated,the isolation rate was 22.2%;the isolation rate among AFP cases with zero dose immunization was higher than those among the children with 1-2 doses and 3 doses;the PVⅡ isolation rate of 79 residue paralysis cases after onset of disease for 60 days was accounting for 7.59%.Conclusion The monitor of laboratory about AFP cases was perfect,doing well in both routine immunization and strengthening immunization are important,PVⅡ was a pathogenic cause for them that haven’t complete immunization.