阿托伐他汀对进展性脑梗死神经功能的影响

Inflence of Atorvastatin in Progressive Neurological Function of Cerebral Infarction

目的探讨阿托伐他汀对进展性脑梗死神经功能的影响。方法本组病例来自2008年1月—2010年1月收治的进展性脑梗死216例,随机分为常规治疗组100例,阿托伐他汀组116例,观察两组神经功能评分变化和血脂变化。结果经统计学分析,两组病例进行神经功能评分比较P<0.05有显著差异性。两组治疗前血脂比较P>0.05无显著差异性。两组治疗后血脂比较P<0.05有显著差异性。结论治疗进展性脑梗死中应用阿托伐他汀能够有效的改善和促进神经功能恢复,促进疾病的康复,明显降低血脂浓度,防止脉粥样硬化斑块破裂,减轻血栓形成反应。

Objective To evaluate the progress of atorvastatin on neurological function of cerebral infarction. Methods The patients from January 2008 - 2010 January admitted 216 cases of cerebral infarction were randomly divided into conventional treatment group 100 cases and atorvastatin group 116 cases, observed changes and neurological function score lipid levels. Results After statisti- cal analysis, two groups were compared the neural function and P 〈 0.05 significant difference. Comparing the two groups before treatment, blood lipid P 〉 0. 05 no significant difference. After treatment, blood lipids compared P 〈 0.05 significant difference. Conclusion The treatment of progressive cerebral infarction in the application of atorvastatin can effectively improve and promote the recovery of neurological function, and promote the rehabilitation of the disease, significantly lower blood lipid levels to prevent plaque rupture pulse, to reduce thrombosis reaction.