急性脑梗死与血浆同型半胱氨的关系研究

Study of Relations of Acute Cerebral Infarction and Plasma Cysteine

目的探讨急性脑梗死与血浆同型半胱氨酸(Hey)关系及其临床意义。方法选取120例急性脑梗死住院患者和80例同年龄段健康体格检查人群进行血浆Hey、叶酸和维生素B12的测定,并进行比较。结果急性脑梗死组患者血浆Hcy水平明显升高(P<0.01),叶酸、维生素B12水平明显低于对照组(P<0.01)。结论急性脑梗死组患者血浆Hcy升高,而叶酸、维生素B12下降,可以认为同型半胱氨酸血症是急性脑梗死的独立危险因素。

Objective To investigate the acute cerebral infarction and plasma homocysteine （Hey） and its clinical significance. Methods Totally 120 cases of acute cerebral infarction and 80 cases of hospitalized patients health examination of the same age groups for plasma Hey, the determination of folic acid and vitamin B12, and compared. Results The plasma Hey in patients with acute cerebral infarction significantly increased （P 〈0.01 ） , folic acid, vitamin B12 levels were significantly lower than the control group （P 〈 0.01 ）. Conclusion The plasma ttcy in patients with acute cerebral infarction increased, and folic acid, vitamin BI2 decrease, homocysteine is an independent risk factor for acute cerebral infarction.