胃癌病人血清中微量元素的测定与研究

DETERMINATION AND RESEARCH ON LEVELS OF SERUM TRACE ELEMENTS WITH STOMACH CANCER

目的探讨胃癌患者血清微量元素与疾病的关系。方法采用电感耦合等离子发射光谱法对胃癌病人和正常人群血清微量元素进行测定并进行相关性研究。结果胃癌患者血清Cu、Zn、Cr、Se值与正常人群存在显著性差异。该法测定微量元素含量的相对标准偏差全部小于0．3％，加标回收率在95．33％～104．7％之间。结论胃癌组与健康组相比，Cu、Cr高于健康组，Se、Zn均低于健康组。

Objective To investigate the significance of serum trace elements in gastric cancer and its pathogenesis. Methods Gastric cancer patients and healthy human serum trace elements were determined by Inductively Coupled Plasma - Atomic Emission Spectrometry（ICP - AES）. Results The concentration of Cu, Zn, Cr and Se in serum showed significant difference between the gastric cancer patients and healthy individuals. The relative standard division （RSD） was less than 0.3% in all. The recovery rates were between 95.33% - 104.7%. Conclusion Compared with control group, the level of Cr and Cu in gastric cancer is higher, while the level of Se and Zn are lower.