雾化吸入凝血酶治疗支气管扩张大咯血临床观察

目的:探讨雾化吸入凝血酶在支气管扩张大咯血患者中的治疗作用。方法:将支气管扩张大咯血患者52例随机分为观察组和对照组,对照组给予内科常规治疗,观察组在常规治疗的基础上,加行凝血酶雾化吸入治疗。结果:观察组和对照组治疗有效率分别为88.5%、65.4%,平均止血时间分别为2.3±0.31天、3.6±0.52天,观察组治疗有效率显著高于对照组(P<0.05),平均止血时间明显短于对照组(P<0.05)。结论:雾化吸入凝血酶治疗支气管扩张大咯血疗效显著,能缩短止血时间,无痛苦、安全、简单,值得临床推广应用。

Objective：To analyze the application value of aerosol inhalation of thrombin in bronchiectasis complicating large hemoptysis. Methods ：52 patients with bronchiectasis complicating with large hemoptysis were randomly divided into observation group （26cases） and control group（26cases）. The patients in two groups were given routine medical treatment. In addition, the patients in observation group were given aerosol inhalation of thrombin. Results ： In observation group and control group, the efficacious rate for hemostasis was respectively 88.5% and65.4%, the average time for hemostasis was respectively 2. 3 ±0. 31 d and 3. 6 ±0. 52d. There was significant difference be- tween two groups （ P 〈 0. 05 ）. Conclusion ： Aerosol inhalation of thrombin in treatment of bronchiectasis complicating large hemoptysis was effective and safe, and was worth to generalizing the clinical application value.