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妊娠甲亢应用抗甲状腺药物治疗临床观察 被引量:6

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摘要 目的:探讨抗甲状腺药物治疗妊娠期甲亢时对孕妇和胎儿的影响,指导临床治疗。方法:妊娠合并甲亢患者27例,治疗组13例(他巴唑6例,丙基硫氧嘧啶7例),未治疗组14例,对两组孕妇的孕产情况和胎儿健康状况进行比较。结果:治疗组孕妇产前甲状腺功能正常11例,轻度升高2例;足月顺产12例,早产1例;新生儿体重正常11例,超重2例。未治疗组孕妇产前甲状腺功能明显升高11例,正常1例,未查2例;流产及死胎6例,早产6例,顺产2例;新生儿低体重5例。两组新生儿甲状腺功能均无明显异常。结论:妊娠期甲亢合理应用抗甲状腺药物治疗有利于妊娠的顺利进行,对孕妇和胎儿无明显不良影响。
出处 《中国民康医学》 2011年第3期330-330,353,共2页 Medical Journal of Chinese People’s Health
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参考文献7

  • 1乔文颖.甲亢妊娠和胎儿甲亢[J].国外医学(内分泌学分册),2002,22(2):90-92. 被引量:10
  • 2Gingberg,LewanczukRZ,HonoreLH.Hyperplacentosis:a novel cause of hyperthyroidism[J].Thyroid,2001,11(4):393-396.
  • 3李晨阳,滕卫平,尚涛.甲状腺激素与妊娠[J].中华内分泌代谢杂志,2003,19(2):158-160. 被引量:72
  • 4梁干雄,麦建章,李远明,苏园园,张汉奎,郑婉文,陈春贤.丙基硫氧嘧啶治疗剂量对甲亢合并妊娠的新生儿甲状腺功能的影响[J].广东医学,2001,22(11):1067-1068. 被引量:7
  • 5Momotani N,Yamashita R,MakinoF,et al.Thyroid funetion in wholly breast-fereding infants whose mothers take high doses of propylthiouracil[J].clin Fndocrinolloxf,2000,53(2):177-181.
  • 6DroaraKanathCS,AmminiAC,KniplaniA,et al.Graves Disease during pregnancy-results of antithy rood drug therapy[J].Singapore Med,1999,40(2):70-73.
  • 7FerrarMS,ValenziseM,LeroneM,et al.Malformations following methimazole exposure in utero:an open issue[J].Birth Defeets Research.part A,Lincal and Molecular teralology,2003,67(1):989-992.

二级参考文献13

  • 1Chan N N,Lancet,1999年,353卷,9171页
  • 2Orgiazzi J. Anti-TSH receptor antibodies in clinical practice[J]. Endocrinol Metab Clin North Am,2000,29: 339-355.
  • 3Mestman J H. Hyperthyroidism in pregnancy[J]. Endocrinol Metab Clin North Am, 1998,27: 127-149.
  • 4Atkins P, Cohen S B, Phillips B J. Drug therapy for hyperthyroidism in pregnancy: safety issues for mother and fetus[J]. Drug Saf,2000,23:229-244.
  • 5Momotani N, Noh J Y, Jshikawa N, et al. Effects of propylthiouracil and methimazole on fetal thyroid status in mothers with Graves' hyperthyroidism [J]. J Clin Endocrinol Metab, 1997,82:3633-3639.
  • 6Davison S, Lennard T W, Davison J, et al. Management of a pregnant patient with Graves' disease complicated by thionamid-induced neutropenia in the first trimester [J]. Clin Endocrinol (0xf),2001,54:559-561.
  • 7Mestman J H. Diagnosis and management of maternal and fetal thyroid disorders[J]. Curr Opin Obstet Gynecol, 1999,11:167-175.
  • 8Nelson-Piercy C. Treatment of nausea and vomiting in pregnancy,when should it be treated and what can be safely taken? [J]. Drug Saf, 1998,19:155-164.
  • 9Smiths C. Congenital thyrotoxicosis in premature infants[J]. Clin Endocrinol (Oxf),2001,54:371-376.
  • 10. Folgen der Hypothyreose in der Schwangerschaft Haddow JE, Palomaki GE, Allan WC et al. (1999) Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N Engl J Med 341: 549–555[J] 2001,Monatsschrift Kinderheilkunde(1):62

共引文献85

同被引文献65

  • 1吕志萍,董淑萍,梁晨.烟台市新生儿先天性甲状腺功能低下症病因学分析研究[J].中华临床医师杂志(电子版),2011,5(19):5779-5782. 被引量:2
  • 2连小兰,白耀,徐蕴华,戴为信,郭芝生.妊娠合并甲状腺功能亢进症患者抗甲状腺药物治疗后对其新生儿先天畸形的影响[J].中华妇产科杂志,2005,40(8):511-515. 被引量:43
  • 3Momotani N,Noh JY,Ishikawa N. Effects of propylthiouracil and methi-mazole on fetal thyroid status in mothers with Graves'hyperthyroidism[J]. Journal of Clinical Endocrinology and Metabolism, 1997,82 (11):3633-3636.
  • 4Dussault JH,Fisher DA. Thyroid function in mothers of hypothyroid new-borns[J].OBSTETRICS and GYNECOLOGY,1999(1):15-20.
  • 5POLAK M.Hyperthyroidism in early infancy:Pathogenesis clinical fea-tures and diagnosis with a focus on neo-natal hyperthyroidism[J].Thy-roid,1998(8):1171-1177.
  • 6Deanna K True, Michael Thomsett , Helen Liley, et al. Twin pregnancy with a coexisting hydatiform mole and live- born infant: Complicated by maternal hyperthyroidism and neonatal hypothyroidism [ J ]. Journal of Paediatrics and Child Health ( IF 1. 254), 2007,43 (9) : 646 - 648.
  • 7Aggarawal N, Suri V, Singla R, et al. Pregnancy Outcome in Hyperthyroidism: A Case Control Study[ J]. Gynecologic and Obstetric Investigation ,2014,77 (2) :94 - 99.
  • 8Nir Pillar, Amalia Levy, Gershon Holcberg, et al. Pregnan- cy and perinatal outcome in women with hyperthyroidism [ J ]. International Journal of Gynecology & Obstetrics, 2010,108(1) :61 -64.
  • 9李传辉,何皓,左巧富,邹文华.妊娠合并甲状腺功能亢进症67例临床分析[J].中国现代医药杂志,2008,10(6):40-43. 被引量:13
  • 10翁秀琴,秦洁,戴洁,曹华妹,杨虹.妊娠合并甲状腺机能亢进255例临床分析[J].中国优生与遗传杂志,2009,17(11):62-63. 被引量:7

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