早期糖尿病肾病微量白蛋白随意尿与尿定量检测结果比较分析

Analysis of random and 24h urine albumin in patients with early diabetic nephropathy

目的探讨随机尿微量白蛋白检测对筛查早期糖尿病肾病的临床应用价值。方法对100例临床确诊为早期糖尿病肾病患者分别完成24h尿样收集(A组)及白天随机尿的收集(B组);白蛋白测定采用免疫比浊法,对两种不同方法收集尿液的检测结果与临床对比分析总结。结果 A组与B组微量白蛋白尿的检测结果比较无显著性差异(P>0.05)。结论随意尿微量白蛋白定量检测同样适用于早期糖尿病肾病的筛查,此法采集标本简便,检测灵敏度高,可在临床推广应用。

Objective To investigate the value of the detection of albumin in random urine for the screening of early diabetic nephropathy.Method Immune turbidimetry was used to exam 24h urine（group A） and random urine albumin（group B）in 100 patients diagnosed with early diabetic nephropathy respectively and the results were compared with clinical data.Results Microalbuminuria content of group B was similar to that of group A,with no significant difference（P0.05）.Conclusion The quantitative analysis of random urinary albumin was equally applicable to the screening of early diabetic nephropathy.With specimens easily collected and high sensitivity,this method could clinically applied.