期刊文献+

尿微量白蛋白测定在早期糖尿病肾病中的应用 被引量:10

Clinical application of micro-urine albumin assay on early diabetic nephropathy
下载PDF
导出
摘要 目的:探讨尿微量白蛋白对糖尿病肾病早期肾损害的诊断价值。方法:采用免疫比浊法,在日立全自动生化分析仪上测定120例糖尿病患者的尿微量白蛋白,并与40例正常健康者的测定结果进行比较。结果:120例糖尿病患者中检出尿微量白蛋白者35例,检出率为29.2%,检测40例正常对照者,1例检出尿微量白蛋白,检出率为2.5%。二者比较,差异有统计学意义(P<0.01)。结论:糖尿病患者尿微量白蛋白检出率高,定期对糖尿病患者检测尿微量白蛋白的排出量,对发现糖尿病肾病早期肾损害有重要的诊断价值。 Objective: To research the diagnostic value of micro-urine albumin in diabetic nephropathy in the early renal damage.Methods: The first morning urine was collected,and the micro-urine albumin was determined by immune transmission turbidity and using Hitachi full automatic biochemical analyzer in 120 diabetic patients and 40 control subjects.Results: Among 120 diabetic patients,35 cases(29.2%) had micro-urine albumin in urine,among 40 cases of the normal control group,1 case(2.5%) had micro-urine albumin,there was a significnat difference in the two groups(P0.01).Conclusion: There is a high incidence for diabetes mellitus with micro-urine albumin,regular examination of the removal amount of micro-urine albumin in diabetic patients has a very significant diagnostic value to find diabetic nephropathy in the early renal damage.
作者 杨小东
出处 《中国医药导报》 CAS 2011年第4期36-37,共2页 China Medical Herald
关键词 尿微量白蛋白 糖尿病 肾损害 Micro-urine albumin Diabetes Renal damage
  • 相关文献

参考文献6

二级参考文献25

  • 1向振秀,许辉,张军,杨敬华,周巧玲.尿视黄醇结合蛋白对糖尿病肾病早期诊断的意义[J].中国现代医学杂志,2004,14(17):128-129. 被引量:10
  • 2乔玉峰,庞东梓,张志利,蒋云生.糖尿病肾病早期诊断指标研究进展[J].国外医学(泌尿系统分册),2005,25(5):670-673. 被引量:13
  • 3胡波 许珏 陈忠诚等.Ⅱ型糖尿病患IL-6、TNFa水平检测.中华临床医学研究杂志,2004,10(2):448-449.
  • 4康会书 房杨 王玥等.三种尿微量蛋白联合检测糖尿病患者的临床意义.中华检验医学杂志,2005,28(3):197-200.
  • 5龙三太 龙五福.桥联ABC-ELISA夹心法检测Ⅱ型糖尿病的临床研究.中华检验医学杂志,2003,26(2):101-103.
  • 6Gilbert RE,Cooper ME.The tubulointerstitum in progressive diabetic kidney disease:more than an aftermath of glonerular injury[J].Kidney Int,1999,56(5):1627-1637.
  • 7Jaconi S,Rose K,Hughes GJ,et al.Characterization of two post-translationally processed forms of human serum retinol-binding protein:altered ratios in chronic renal failure[J].J Lipid Rescarch,1995,36(6):1247-1253.
  • 8Smith GC,Winterboru MH,Taylor CM,et al.Assessment of retinalbinding protein excretion in normal children[J].Pediarr Nephrol,1994,8(2):148-150.
  • 9Ellis D,Forrest KY,Erbey F,et al.Urinary measurement of transforming growth factor-β and type Ⅳ collagen as new markers of renal injury:application in diabetic nephropathy[J].Clin Chem,1998,44(5):950-956.
  • 10姚建.肾小管标志蛋白及其临床意义[J].中华肾脏病杂志,1997,13(2):113-115. 被引量:135

共引文献70

同被引文献68

引证文献10

二级引证文献40

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部