58例骨与软组织恶性肿瘤介入治疗——临床、影像与病理综合评价

Interventional therapy of 58 cases of malignant bone and soft tissue tumors: clinical, radiographic and pathological evaluations

目的探讨骨与软组织肿瘤介入治疗的技术和疗效及血管造影表现在评价疗效方面的意义。材料与方法５８例骨与软组织肿瘤患者接受介入治疗，并随访３～２４个月，观察临床及放射学改善情况，计算肿瘤坏死百分比并与血管造影表现对照。结果治疗后大部分患者临床指标明显改善，肢体肿瘤患者９２％行保肢手术，术后局部复发率为１３．６％。手术病理示５３％（１０／１９）的患者肿瘤坏死率达９０％以上，术后血管造影表现与病理结果相符。结论介入治疗是骨与软组织肿瘤治疗的有效方法，血管造影是判断疗效及预后的可靠指标。

Objective To assess the value of transarterial infusion chemotherapy and transarterial embolization in the treatment of malignant bone and soft tissue tumors. Materials and Methods 58 cases of malignant bone and soft tissue tumors were included with clinical and radiographic follow up, improvement were observed by calculating percentage of necsrotic tumor areas. Results Marked improvement of the symptoms in most patients were noticed. Limb sparing resection was obtained in 92% patients and the local recurrence rate was 13.6%. Tumor necrosis of 90%～100% was revealed in 53%(10/19) of the patients. Significant correlation between angiographic and pathological findings was presented. Conclusion Interventional therapy is a safe and effective procedure in treating malignant bone and soft tissue tumors. Follow up angiographic findings can predict the respones of the patients.