观察氨磷汀对肺癌化疗患者血液学的保护作用

Hematological protective effects of amifostine for lung cancer chemotherapy patients

目的观察氨磷汀对肺癌化疗患者的减轻血液学毒性作用。方法将57例肺癌患者分为对照组（化疗第1周期，未用氨磷汀）和治疗组（化疗第2周期，联用氨磷汀）进行自身对照观察，化疗前后监测血液学毒性。结果化疗后血液学毒性治疗组较对照组明显降低。结论氨磷汀可明显减少肺癌患者化疗相关性血液学毒性。

Objective To study the hematological protective effects of amifostine on lung cancer patients receiving chemotherapy. Methods Fifty - seven patients were treated by two kinds of treatments： one was chemotherapy （control group） , the other was chemotherapy plus amifostine （treatment group）. Hematological toxicity was observed before and after chemotherapy. Results Hematological tox- icity of treatment group reduced obviously, compared with control group. Conclusions Amifostine can apparently reduce the hematological toxicity of patients receiving chemotherapy.