期刊文献+

46例IgA肾病患者肾脏病理表现与中医辨证分型的相关性研究 被引量:10

Correlation study between renal pathology and differentiating typing of TCM in 46 patients wth IgA nephropathy
下载PDF
导出
摘要 [目的]研究IgA肾病在光镜下的病理表现(Lee氏分级)与中医辨证分型的相关性。[方法]收集已做肾活检,经免疫荧光病理检查确诊为IgA肾病的46例住院患者,记录每个患者的光镜病理表现,并进行中医辨证分型。[结果]IgA肾病病理表现和中医辨证相关(P<0.01)。肾脏病理表现采用Lee氏分级法,其中Lee氏Ⅰ级、Lee氏Ⅱ级中医证型多为热毒内扰和(或)湿热壅滞;Lee氏Ⅲ级、Ⅳ级中医证型多为脉络瘀阻和(或)虚实夹杂;Lee氏Ⅴ级中医证型为虚实夹杂,因例数少而无统计学意义。[结论]IgA肾病的病理表现与中医的辨证分型有一定的相关性,微观变化与中医辨证结合拓展了中西医结合诊治IgA肾病的思路。 [Objective] To study the correlation between pathologic appearances under light microscopy in IgA kidney disease(Lee's classification) and TCM syndrome differentiation.[Methods] Fourty-six patients diagnosed as IgA nephropathy via renal immunofluorescence pathology were collected,recording their pathologic changes under light microscopy and making differentiated typing.[Results] The IgA kidney pathological appearance and its TCM syndrome differentiation were correlated.(P0.01).Renal pathology grading was performed by Lee's classification method.Among them,more patients with Lee's Ⅰ,Lee's Ⅱ had TCM syndrome type of inner disorder of toxic heat and(or) humid warm obstruction,while patients with Lee's Ⅲ level or Ⅳ level had blockage of the vessel and(or) deficiency syndrome mingling with excess syndrome and Lee's Ⅴ level had deficiency syndrome mingling with excess syndrome.It was not statistical significant because less number.[Conclusion] There are some correlation between IgA kidney pathology and TCM syndrome.Micro-change and the combination of TCM syndrome differentiation may expand the diagnosis and treatment of IgA nephropathy.
出处 《天津中医药》 CAS 2011年第1期22-23,共2页 Tianjin Journal of Traditional Chinese Medicine
关键词 IGA肾病 病理表现 辨证分型 IgA nephropathy pathology differentiation of symptoms and signs for classification of syndrome
  • 引文网络
  • 相关文献

参考文献3

二级参考文献16

  • 1黎磊石,俞雨生,王金泉.IgA肾病诊断及治疗规范[J].肾脏病与透析肾移植杂志,2004,13(3):253-255. 被引量:62
  • 2刘刚,马序竹,邹万忠,王梅,王海燕.肾活检患者肾脏病构成十年对比分析[J].临床内科杂志,2004,21(12):834-838. 被引量:182
  • 3王永钧,陈洪宇.IgA肾病中西医结合诊断及治疗建议[J].中国中西医结合肾病杂志,2005,6(2):63-66. 被引量:25
  • 4王海燕.肾脏病学[M].北京:人民卫生出版社,1997.684.
  • 5Li LS, Liu ZH. Epidemiologic data of renal diseases from a single unit in China: analysis based on 13 519 renal biopsies. Kidney Int, 2004,66((3)) :920 - 923.
  • 6Lee SM, Rao VM, Franklin WA, et al. lgA nephropathy: morphologic predictors of progressive renal diseases. Hum Pathol, 1982,13(4) :314 - 322.
  • 7Katafuchi R, Kiyoshi Y, Oh Y, et al. Glomerular score as a prognosticator in IgA nephropathy: its useful- ness and limitation. Clin Nephrol, 1998,49( 1 ) : 1 - 8.
  • 8Andreoli SP, Bergstein JM. Treatment of ,severe IgA nephropathy in children. Pediatr Nephrol, 1989,3(3) :248 - 253.
  • 9Levey AS, Atkins R, Coresh J, et al. Chronic kidney disease as a global public health problem:approaches and initiatives- a position statement from Kidney Disease Improving Global Out- comes. Kidney Int,2007,72(3) :247 - 259.
  • 10Schena FP.IgA Nephropathies.In Cameron JS,Davison AM.Oxford Textbook of Clinical Nephrology.Oxford:Oxford University Press,1992:339-369.

共引文献86

同被引文献152

引证文献10

二级引证文献34

;
使用帮助 返回顶部