摘要
目的观察氟哌啶醇静脉注射对兔房水动力学的影响。方法３０只家兔被随机分为１．０％氟哌啶醇组、２．０％氟哌啶醇组和溶剂对照组，用房水荧光浓度测定法测定各组静脉注射相应药剂后的正常前房水相对荧光素钠浓度（ＲＦＣ）、先期用药ＲＦＣ及后期用药ＲＦＣ。结果氟哌啶醇静脉注射可明显地抑制房水的生成，１．０％的浓度即可达到有效作用，提高浓度并不增加药效。氟哌啶醇不影响房水的排出。结论氟哌啶醇静脉注射可以有效地抑制兔眼房水生成。
ObjectiveToobservetheeffectofintravenoushaloperidol(HAL)onrabbitsaqueoushumourdynamics.Methods30rabbitswererandomlydividedinto1.0%HALgroup,2.0%HALgroupandvehiclegroup.Thenormalrelativefluorescentconcentration(RFC)inanteriorchamber,RFCwithintravenousHALorvehiclebeforeiv.fluoresceinandRFCwithintravenousHALorvehicleafteriv.fluoresceininthethreegroupsweremeasuredbyfluoresceinphotometer.ResultsIntravenousinjectionof1.0%HALcansignificantlyimpresstheformationofaqueoushumour.Higherconcentrationcantincreasetheimpressingeffect.Thedrugdidntaffectthedrainageofaqueoushumour.ConclusionHALcaneffectivelyimpresstheinformationofrabbbitsaqueoushumour.
出处
《眼科研究》
CSCD
1999年第3期175-176,共2页
Chinese Ophthalmic Research
关键词
氟哌啶醇
静脉注射
房水动力学
兔
眼压
haloperidolintravenousinjectionaqueoushumourdynamicsrabbit
