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替吉奥胶囊联合顺铂、多西紫杉醇治疗晚期胃癌的临床观察 被引量:12

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摘要 【目的】观察替吉奥胶囊(S-1)联合顺铂、多西紫杉醇治疗晚期胃癌的近期疗效和不良反应。【方法】全组42例患者,均经病理检查确诊为腺癌,给予S-1联合顺铂、多西紫杉醇治疗,方案为:S-140mg,口服,一天两次,d1~14;顺铂25mg/m^2,d1-3静脉滴注;多西紫杉醇75mg/m^2,d.静脉滴注。每3周重复。2周期后评价疗效。【结果]42例患者总有效率为40.4%;中位无进展生存期5.5个月,1年生存率38.3%;主要不良反应是骨髓抑制和胃肠道反应。【结论】S-1联合顺铂、多西紫杉醇治疗晚期胃癌疗效确切、安全。
出处 《医学临床研究》 CAS 2011年第1期130-131,共2页 Journal of Clinical Research
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