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胰腺癌的靶向治疗

Targeted therapies for pancreatic cancer
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摘要 放化疗联合靶向药物治疗是晚期胰腺癌的主要治疗手段.目前与胰腺癌治疗相关的靶向药物主要有表皮生长因子受体(EGFR)阻断剂、抗血管内皮生长因子(VEGF)单克隆抗体等.其中,厄洛替尼与吉西他滨(GEM)联合已被证实具有延长胰腺癌患者生存期的作用. The combination of chemotherapy, radiotherapy and targeted therapies are considered to be major treatments for metastatic pancreatic cancer. At present, the target therapy-related medications include mainly antagonist of epidermal growth factor receptor, monoclonal antibody of vascular endothelial growth factor and so on. Erlotinib combined with gemcitabine has been demonstrated to prolong the survival of patients with pancreatic cancer.
作者 顾飞英 袁瑛
出处 《国际肿瘤学杂志》 CAS 2011年第2期148-151,共4页 Journal of International Oncology
关键词 胰腺肿瘤 蛋白酪氨酸激酶类 单克隆抗体 Pancreatic neoplasms Protein-tyrosine kinases Monoclonal antibodies
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参考文献27

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