肺部疾病患者鲍曼不动杆菌的分布及耐药性分析

Distribution and Drug-Resistant of Acinetobacter baumannii isolated from Patients of Lung Disease

目的分析鲍曼不动杆菌（AB）在本院肺癌及肺结核患者中分布特点及其耐药谱。方法分离自2007～2009年本院肺癌及肺结核患者不同标本的AB经GNI鉴定卡确认后，测定分离菌株对14种抗菌剂的敏感性。结果共分离216株AB临床菌株，分离率及AB对常用抗菌剂的耐药率呈逐年上升趋势。检出9株AB对所有受试抗菌剂耐药，所对应患者均符合呼吸机相关性肺炎的诊断。结论在研究AB泛耐药株耐药机制的同时，需加大对其所感染宿主的研究力度。

Objective To explore the distribution and drug resistant profile of Acinetobacter baumannii （AB）from patient with lung cancer or pulmonary tuberculosis. Methods AB was isolated from patients during 2007 and 2009. After identified by GNI card,the susceptibility of isolated AB to 14 antibacterial agents were detected. Results 216 strains of AB were collected. Separation rate and drug resistant rate of AB were gradually increasing within the three years. 9 strains of AB, resistant to all tested antibacterial agents,were detected and all corresponding patients were diagnosed with ventilator-associated pneumonia. Conclusion When drug resistance mechanisms of AB were studied,the research about AB-infected host should also be the focused.