心肌酶谱应用于儿童反复上呼吸道感染诊断的临床价值

Clinical Value of Myocardial Enzyme Detection in Upper Respiratory Tract Infection Patients

目的探讨心肌酶谱测定在反复上呼吸道感染(RURI)患儿临床诊断中的应用价值。方法参照相关诊断标准,将324例上感患儿分为RURI组、普通上呼吸道感感染(CURI)组以及高热上呼吸道感染(HURI)组、非高热上呼吸道感染(NHU-RI)组,测定并分析血清心肌酶谱相关指标。结果 RURI组患儿血清心肌酶谱指标较CURI组高,差异有统计学意义(P<0.05);HURI组患儿较NHURI组高,差异有统计学意义(P<0.05)。结合临床诊断资料,1例诊断为心肌炎,16例诊断为亚临床心肌炎,8例疑诊心肌炎。结论 RURI及HURI患儿心肌细胞有不同程度损伤;常规检测患儿心肌酶谱,对心肌炎及亚临床心肌炎的早期诊断有重要临床意义。

Objective To determine enzymogram repeated upper respiratory tract infection in patients with clinical value,in order to provide reference for clinical diagnosis. Methods Randomly selected 324 cases of upper respiratory tract infection in children hospitalized were used for serum myocardial enzymes （AST, LDH, CK, CK-MB, α- HBD） determination, based on the annual number of upper respiratory tract infection, upper respiratory tract with reference to the diagnostic criteria and repeated on diagnostic crite- ria for respiratory tract infections would be difficult to measure the object is divided into repeated upper respiratory tract infection group and the ordinary upper respiratory tract infection group, on the ordinary sense of group as the control group, and then com- bined according to whether patients with a high fever,high fever will be determined on the object is divided into experimental group and control group determination of the results of two clinical analysis. Results Repeated upper respiratory tract infection group has higher serum enzymes than common upper respiratory tract infection group. （P^0. 05） ;serum enzymes in patients with high fever group study are higher than the control group（P^0.05）. Combined with the clinical diagnostic data,there is one clinical diagnosis of myocarditis;16 cases were diagnosed as subclinical myocarditis;8 cases of suspected myocarditis. COnclusion Myocardial cells have been damaged in repeated upper respiratory tract infection patients and those with high fever, upper respiratory tract infection. Routine testing of serum myocardial enzymes, have important clinical significance on the early detection of patients with myocarditis and subclinical myocarditis.