气管切开患者下呼吸道革兰阴性杆菌感染流行病学调查

The Epidemology Investigatioin of Gram-Negative Bacilli in Patients with Lower Respiratory Tract Infection after Tracheotomy

目的了解重症监护病房(ICU)气管切开患者革兰阴性杆菌感染情况及细菌耐药性。方法回顾2002年6月至2007年6月从本院ICU气管切开患者痰标本分离的革兰阴性杆菌分布情况,并对药敏结果进行分析。结果分离获得革兰阴性杆菌232株,以铜绿假单胞菌(28.9%)和鲍曼不动杆菌(20.3%)为主,不同菌种具有不同的抗菌剂耐药性。结论气管切开患者下呼吸道感染病原菌以革兰阴性杆菌为主,应根据药敏试验结果合理选用抗菌剂。

Objective To understand the information of patients in intensive care unit（ICU）with tracheotomy and infected by gram-negative bacilli and resistance to antibacterial agents. Methods Distribution and drug resistance of gram-negative bacill isola- ted from antibacterial agent sample of patients in ICU with tracheotomy between June 2002 to June 2007 was analyzed. Results 232 strains of gram-negative bacilli were collected,most of which were Pseudomonas aeruginosa （28. 9%）and Acinetobacter baumannii （20.3 %）. Different strains have different resditance to antibacterial angents. Conclusion Most pathogens,causing lower respiratory tract infection in patients with tracheotomy,are gram-negative bacilli and the results of antibiotic sensitivity test should he applied for rational use of antibacterial agents.