摘要
目的探讨恒定负荷急性运动训练对大鼠血清白细胞介素活性的影响,试图为运动对免疫的影响提供实验依据。方法对雄性3月龄SD大鼠一次恒定负荷急性运动后即刻3、h7、2 h点及对照组断头取血,测定白细胞介素1(IL-1)、白细胞介素2(IL-2)、白细胞介素6(IL-6),并进行统计学分析。结果与对照组相比,一次急性运动后即刻IL-1升高(P<0.01),运动后3 h较运动后即刻有所下降(P<0.05),但仍然高于对照组(P<0.05),运动后72 h恢复到对照组水平(P>0.05)。运动后即刻及运动后3 h大鼠IL-6水平均高于对照组(P<0.01),且运动后3 h高于运动后即刻(P<0.05),运动后72 h恢复到对照组水平(P>0.05);急性运动后即刻3、h、72 h和对照组之间IL-2水平差异均无统计学意义(P>0.05)。结论 IL-1和IL-6水平与恒定负荷运动存在联系,有先升后降的变化趋势,并且运动后3 h尚不能恢复到安静时水平,72 h可恢复到安静时水平。
Objective To discuss the effects of constant loading acute exercise training on the interleukin activity of rats＇ serum,and to provide experimental basis for the effect of exercise on the immune system.Method 3-month-old SD rats were divided into immediately-after-exercise group,3-hours-after-exercise group,72-hours-after-exercise group and static control group.After a period of constant loading exercise,rats＇ heads were cut and blood was collected.Interleukin-1,Interleukin-2 and Interleukin-6 were tested and statistically analyzed.Results Compared with the control group,IL-1 of the immediately-after-exercise group rose（P0.01）;compared with the immediately-after-exercise group,IL-1 of 3-hours-after-exercise group fell（P0.05）,but remained still higher than the control group（P0.05）;IL-1 of 72-hours-after-exercise group returned to the level of the control group（P0.05）.IL-6 of both the immediately-after-exercise group and the 3-hours-after-exercise group were higher than the control group（P0.01）,and IL-6 of the 3-hours-after-exercise group was higher than that of the immediately-after-exercise group（P0.05）.IL-6 of the 72-hours-after-exercise group returned to the level of the control group（P0.05）.Difference in IL-2 among the groups was not statistically significant（P0.05）.Conclusion IL-1 and IL 6 are related with constant loading acute exercise,and fall after rises.They do not return to the level of static state in 3 hours after exercise until 72 hours after it.
出处
《保健医学研究与实践》
2011年第1期4-6,共3页
Health Medicine Research and Practice
