新生儿高胆红素血症的临床分析

Clinical Analysis of Hyperbrilirubinemia in Neonates

目的探讨新生儿高胆红素血症的病因及治疗方法,为临床早诊断早治疗提供参考依据。方法回顾性分析我院于2009年1月至2010年6月收治的高胆红素血症患儿的临床资料。结果新生儿高胆红素血症病因复杂,包括围产因素(33.3%)、感染因素(23.8%)、母乳性黄疸(17.5%)、非感染因素(11.1%)、其它原因不明者(9.5%)、ABO溶血病(4.8%)。治疗前血清总胆红素水平为(298±45)μmol/L,治疗后为(228±60)μmol/L,治疗前后血清总胆红素水平有显著性差异(P<0.01)。结论加强对新生儿高胆红素血症的病因诊断,做到早预防、早诊断、早治疗,尽可能减少新生儿高胆红素血症。

Objective To investigate the causes,treatment and interferences of hyperbilirubinemia in neonates.Methods The clinical data of 126 patients were analyzed retrospectively.Results The causes included perinatal agent（33.3%）,infection （23.8%）,breast milk jaundice （17.5%）,non-infection（11.1%）,no reason （9.5%）,ABO homolysis （4.8%）.The level of serum total bilirubin before treatment were （298±45）μmol/L which is different with the level after treatment （228±60）μmol/L（P0.05）.Conclusion Rational breast milk jaundice,reduction in perinatal infection,early diagnosis,and early interference are important for hyperbrilirubinemia in neonates.