反复发作躁狂症与双相情感障碍躁狂相的血液流变学特点比较

The hemorrheological changes of manic episode(recurrent) and bipolar affective disorder(manic phase)

目的探讨反复发作躁狂症与双相情感障碍躁狂相的血液流变学特点。方法对住院患者在三天内进行采血检测，利用电脑对三者血液流变学数据进行比较研究。结果反复发作躁狂症全血粘度、刚性指数比正常健康人高（Ｐ＜００５），而血浆压积却比正常健康人低（Ｐ＜００１）；双相情感障碍躁狂相各项指标与正常健康人无显著差异（Ｐ＞００５）；反复发作躁狂症全血粘度、细胞压积、低切还原粘度比双相情感障碍躁狂相高（Ｐ＜００５），而血小板粘附率和血浆压积反之较低（Ｐ＜００５）。结论检查血液流变学性质，有助于躁狂症的分型和对两者病因学的研究。

Objective To study the character of the hemorrheological changes of manic episode(recurrent) and bipolar affective disorder(manic phase).Methods A prespective study in 18 manic episode(recurrent) and 16 bipolar affective disorder(manic phase) and 60 healthy.Results The whole blood viscosity,stiffness index in patients are higher than that of in the healthy(P<0.05).The hemorrheological are no significant differences in ipolar disorder affective(manic phase)and healthy(P>0.05).But the whole blood viscosity,hematocrit and reduced viscosity in manic episode(recurrent)are higher than that of in the bipolar affective disorder(manic phase)(P<0.05).Conclusion The hemorrheological changes are helpful for diagnosing of pathophysiology and type of analysis in manic episode(recurrent) and bipolar affective disorder(manic phase).