思美泰治疗药物性瘀胆型肝炎疗效观察

目的:探讨思美泰(腺苷蛋氨酸)对药物性瘀胆型肝炎的疗效。方法:将62例药物性瘀疸型肝炎随机分两组,治疗组34例和对照组28例。治疗组在一般保肝治疗基础上加用腺苷蛋氨酸1000mg溶于5%葡萄糖20ml,1次/日,静滴。对照组予一般保肝治疗,疗程均4周。结果:治疗4周时,治疗组有效率明显高于对照组,差异有统计学意义(P<005)。结论:思美泰在治疗药物性瘀胆型肝炎上有较好疗效。

Objective：To evaluate the efficacy of ademetionine for treatment of cholestatic hepatitis induced by drugs Methods：62 patients with drug induced cholestatic hepatitis were randomly divided into treatment group（n = 34） and control group（n = 28） The liver protectant therapy combined with ademetionine 1000mg in 5% glucose solution of 20 ml were given by intravenous injection qd in the treatment group for 4 weeks The control group received liver protectant therapy only Results：The combined treatment was more effective in the treatment group than the control group after 2 weeks of treatment（ P 0 05） Conclusion： Ademetionine is an effective drug in the treatment of patients with drug induced cholestatic hepatitis