深圳市宝安区出生缺陷产前诊断现状与策略

目的:了解深圳市宝安区出生缺陷及产前诊断现状,提出提高产前诊断率的对策。方法:回顾性统计深圳市宝安区2003～2009年出生缺陷情况,统计分析出生缺陷率、出生缺陷发生顺位与构成比及产前诊断情况。结果:274152例围产儿中有4248例出生缺陷儿,出生缺陷发生率1548‰;出生缺陷儿中先天性心脏病的构成比最高(2519%);产前诊断的出生缺陷儿有722例(1699%),产前诊断率最高的出生缺陷疾病为脑发育严重畸形(7679%,172/224)。结论:深圳市宝安区出生缺陷发生率居高不下,产前诊断率偏低,建立区属产前诊断中心已是势在必行。

Objectives：Elevating the strategy of prenatal diagnosis ratio based on the status of birth defect and prenatal diagnosis in Baoan,Shenzhen Methods：Retrospectively, analyzing the rate of birth defect,prenatal diagonosis information and the constituent ratio of birth defect between 2003 and 2009 in Bao An ShenZhen Results：274152 perinatal children have 4248 birth defect The incidence of birth defect are 15 48‰,the highest constituent ratio is congenital heart disease（25 19% ）,722 samples（16 99% ） are birth defect children through prenatal diagnosis,the maximal rate of birth defect disease in prenatal diagnosis is Brain deelopment serious deformity （ 76 79% ,172 / 224） Conclusions： The incidence of birth defect is high and the rate of prenatal diagnosis is low in the past,it is necessary to set up a district prenatal diagnosis center