卒中后抑郁患者的多项睡眠图研究

Polysomnographic research on patients with post-stroke depression

目的：探讨多项睡眠图（PSG）各项指标对卒中后抑郁（PSD）患者的诊断价值。方法：卒中后抑郁组（PSD组）和卒中后无抑郁组（对照组）以年龄1：1配对，用PSG仪对两组各59例患者进行整夜睡眠描记并对结果进行分析。结果：睡眠进程：PSD组睡眠潜伏期延长，觉醒时间增多，睡眠总时间减少，睡眠效率下降，睡眠维持率下降，两组比较差异有统计学意义；非快速眼动睡眠（NREM）：PSI）组S1增多，S2减少，但S3＋S4两组比较差异无显著意义；快速眼动睡眠（REM）：PSD组REM潜伏期缩短，REM时间减少，REM周期数减少。结论：PSI）患者存在PSG指标变化，PSG对PSD的诊断和鉴别诊断有临床价值。

Objective： To explore the value of polysomnography（PSG） in the diagnosis of poststroke depression（PSD）. Methods： The 1 to 1 pair study of was conducted in 59 patients with PSD （PSD group） and 59 stroke patients without depression（the control group）. The two groups were matched by age. The whole night PSG was recorded from patients of both groups. The results were compared. Re- suits： Patients with PSD prolonged sleep latency,increased arousal time and decreased total sleep time, decreased sleep efficiency and sleep maintenance. There was significant difference between the two groups. In NREM, patients with PSD increased percentage of Stage 1 sleep, decreased percentage of Stage 2 sleep,but the percentage of Stage 3 plus Stage 4 sleep had no significant difference between the two groups. In REM , REM latency was shortened and REM time was reduced and the number of REM period was reduced in PSD group. Conclusion： There might be changes of PSG indexes in patients with PSD. PSG has clinical value in the diagnosis and differential diagnosis of PSD.