婴幼儿轮状病毒肠炎血清心肌酶谱测定的临床意义

Clinical significance of serum myocardial enzyme spectrum in children with rotavirus enteritis

目的：探讨婴幼儿轮状病毒（RV）肠炎血清心肌酶谱的变化及临床意义。方法：回顾性分析我院2008年1月~2009年12月收治的208例婴幼儿RV肠炎的临床资料。结果：RV肠炎组208例RV肠炎患儿血清心肌酶谱活性均明显高于196例急性腹泻组患儿。伴代谢性酸中毒和水、电解质失衡的98例RV肠炎患儿心肌酶谱较其他110例RV肠炎患儿升高明显。治疗7天后复查心肌酶谱,多数患儿恢复正常。结论：心肌酶谱测定对婴幼儿RV肠炎的诊断、监测病情变化及指导治疗有重要的临床意义。

Objective：To investigate the clinical significance and changes of serum myocardial enzyme spectrum in children with rotavirus enteritis.Methods：We retrospectively reviewed 208 children with rotavirus enteritis treated in our hospital from Jan.2008 to Dec.2009,and studied the enzyme spectrum,electrocardiography and so on by statistical analysis.Results：The serum myocardial enzyme activity in 208 children with rotavirus enteritis（observation group） was higher than that in 196 children with acute diarrhea（control group）.The activity of serum myocardial enzyme was higher in 98 children with rotavirus enteritis complicating metabolic acidosis and electrolyte imbalance than that in other 110 children with rotavirus enteritis（P0.01）.The serum myocardial enzyme activity in most of children patients with rotavirus enteritis was recovered to normal after 7 d.Conclusion：Myocardial enzymatic determination of children with rotavirus enteritis has important clinical significance to diagnosis,monitoring disease condition change and guiding treatment.