摘要
目的比较粘鱼须、威灵仙、棉团铁线莲对细胞免疫和体液免疫的影响,为粘鱼须作为威灵仙入药提供科学依据。方法选择影响玫瑰花环形成、T细胞亚群数量、迟发型变态反应等3个细胞免疫的指标和影响抗体形成细胞数量、血清溶血素数量等2个体液免疫的指标进行比较。结果粘鱼须、威灵仙、棉团铁线莲均能抑制T细胞功能,降低机体细胞免疫反应能力。结论粘鱼须可以作为祛风湿药威灵仙使用。
Objective To compare the effects of Smilax sieboldii Miq.,Clematis chinensis Osbeck.and C.hexapetela Pall on cellular and humoral immunity,and further determine the feasibility of Smilax sieboldii Miq.to be used as a drug. Methods Three cellular immune indexes including the formation rate of erythrocyte rosette,amount of T cell subsets and effects on delayed type hypersensitivity;two humoral immnue ones including the number of plaque forming cell（PFC） and amount of serum hemolysin were compared. Results All of Smilax sieboldii Miq.,Clematis chinensis Osbeck.and C.hexapetela Pall decoction were able to inhibit the activity of T-lymphocyte and reduce the humoral immune function. Conclusion Smilax sieboldii Miq.can be used equivalently as Clematis chinensis Osbeck.for the treatment of rheumatism.
出处
《医药导报》
CAS
2011年第2期163-166,共4页
Herald of Medicine
基金
山东省卫生科技发展计划课题(基金编号:1990032)
关键词
粘鱼须
威灵仙
棉团铁线莲
细胞免疫
体液免疫
Smilax sieboldii Miq.
Clematis chinensis Osbeck.
C.hexapetela Pall
Cellular immunity
Humoral immunity
