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干细胞标志物CD166在大肠癌中的表达及其临床意义 被引量:2

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摘要 目的检测肿瘤干细胞标志物CD166在大肠癌的表达,探讨其临床意义。方法用RT-PCR检测23例手术切除病理确诊的大肠癌组织CD166 mRNA的阳性率和表达水平,并和正常大肠组织对照,分析其与临床和病理各参数的相关性。结果大肠癌组织CD166 mRNA表达的阳性率为95.7%,表达水平为0.309±0.145,均显著高于正常大肠组织的39.1%和0.109±0.255(P<0.01),其表达率与表达强度与患者的年龄、性别、临床分期、肿瘤部位、肿瘤大小、病理分型等均无相关关系(P>0.05)。结论肿瘤干细胞标志物CD166在大肠癌中高表达,其表达与临床和病理参数不相关。
出处 《广东医学》 CAS CSCD 北大核心 2011年第2期201-203,共3页 Guangdong Medical Journal
基金 广州市中西结合科研立项项目(编号:2009-B-01)
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同被引文献18

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