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罗哌卡因硬膜外给药对老年患者顺式阿曲库铵肌松效应的影响 被引量:5

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摘要 目的观察罗哌卡因硬膜外给药对老年患者顺式阿曲库铵肌松效应的影响。方法将全麻复合硬膜外阻滞下行中下腹部手术的老年患者50例随机分为A组及B组,每组25例。A组使用0.75%罗哌卡因分次给药行常规硬膜外阻滞,B组给予生理盐水。两组患者静脉注射依托咪酯、芬太尼及顺式阿曲库铵0.15 mg/kg诱导,持续输注丙泊酚、舒芬太尼和顺式阿曲库铵维持麻醉,术中维持B IS值于40~50之间及T1于10%Tc水平,观察并比较两组患者顺式阿曲库铵肌松效应的变化。结果两组患者顺式阿曲库铵起效时间、恢复指数及TOFR自然恢复的时间无差异,A组临床作用时间较B组明显延长,维持用量亦少于B组(P〈0.01)。结论罗哌卡因硬膜外给药对老年患者顺式阿曲库铵的起效时间及其肌松作用的自然恢复时间无明显影响,但可延长其临床作用时间,并减少其维持用量。
出处 《广东医学》 CAS CSCD 北大核心 2011年第2期220-222,共3页 Guangdong Medical Journal
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二级参考文献2

  • 1徐世元,1993年
  • 2解大建,中华麻醉学杂志,1988年,8卷,4期,195页

共引文献253

同被引文献44

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二级引证文献12

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