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非酒精性脂肪肝相关危险因素的调查分析 被引量:15

Analysis of the risk factors of nonalcoholic fatty liver disease and its preventive measures
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摘要 目的分析非酒精性脂肪肝(NAFLD)的相关危险因素,探讨预防对策。方法以420例NAFLD患者为NAFLD组,与健康对照组对比研究。检测空腹血糖(FBG)、血压、血脂、血尿酸(UA)以及体质量指数(BMI),对以上资料进行相关性分析。结果 NAFLD组各危险因素检出率均高于健康对照组(P<0.05);除高密度脂蛋白胆固醇(HDL-C)外,NAFLD组各临床指标均高于健康对照组(P<0.01);logistic回归模型分析显示BMI、三酰甘油(TG)、HDL-C以及UA是NAFLA的独立危险因素(P=0.000)。结论采取有效干预措施、科学控制BMI、合理膳食、加强体育锻炼可以预防和控制脂肪肝的发生和发展。 Objective To analyze risk factors of nonalcoholic fatty liver disease(NAFLD) and its preventive measures.Methods Fasting blood glucose(FBG),blood pressure,serum lipid,uric acid(UA) and body mass index(BMI) were investigated in 420 NAFLD patients and 420 normal people.Results The risk factors had higher detection rate in NAFLD group than in control group.In addition to high density lipoprotein-cholesterol(HDL-C),all clinical indicators of NAFLD group were higher than that of control group.Multiple logistic regression analysis revealed that BMI、triglyceride(TG)、HDL-C and UA were highly relative to NAFLD.Conclusion Effective intervention,reasonably controlling BMI,rational diet and developing physical training can prevent NAFLD.
作者 吴翠霞
出处 《重庆医学》 CAS CSCD 北大核心 2011年第4期364-365,共2页 Chongqing medicine
关键词 人体质量指数 干预性研究 非酒精性脂肪肝 body mass index intervention studies nonalcoholic fatty liver disease
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