高频彩色多普勒超声对类风湿关节炎早期手指关节骨质侵蚀的诊断价值

Diagnostic value of high-frequency ultrasonography on early stage bone erosion of rheumatoid arthritis knuckles

目的探讨高频彩色多普勒超声对类风湿关节炎(RA)早期手指关节骨质侵蚀的诊断价值。方法对早期RA肿痛指关节分别做高频彩色多普勒超声、X线片、MRI检查,并与健康组对比分析。结果 (1)疾病组与健康组对比超声结果有显著差异。高频彩色多普勒超声检出骨侵蚀关节273个,占56.2%;X线片检出骨侵蚀关节66个,占13.6%;MRI检出骨侵蚀关节277个,占57.0%。(2)对X线片检查无骨侵蚀的420个指关节,以MRI结果为金标准,对高频彩色多普勒超声做诊断评价,其灵敏度为96.3%,特异度为95.8%,准确度为96.1%。结论高频彩色多普勒超声能准确显示RA早期指关节骨质侵蚀。

Objective To discuss the diagnostic value of high-frequency ultrasonography on rheumatoid arthritis knuckles with early stage bone erosion.Methods Comparative analysis of patients with early rheumatoid arthritis swelling and pain knuckles were examined through high frequency ultrasonic scanning,X-ray and MRI examinations.Results（1） There were significant differences between the disease group and the healthy group.The results of high-frequency ultrasonography showed 273 persons positive,accounting for 56.2%;X-ray showed 66 persons positive accounting for 13.6%,and MRI detected 277 persons positive,accounting for 57.0%.（2） Among the 420 X-ray negative knuckles,the sensitivity and specificity of high-frequency ultrasonography were 96.3% and 95.8% based on MRI results as gold standard,respectively.Conclusion High frequency ultrasonography can accurately diagnose bone erosion of knuckles in early rheumatoid arthritis.