摘要
探讨结直肠癌患者红细胞免疫功能和 Ｔ淋巴细胞亚群的变化。方法： 以红细胞 Ｃ３ｂ 受体花环率、红细胞免疫复合物花环率、肿瘤红细胞花环率及 Ｃ Ｄ＋３ 、 Ｃ Ｄ＋４ 、 Ｃ Ｄ＋８ 细胞为观测指标， 测定２６ 例结肠癌和３６ 例直肠癌患者的免疫功能， 并与３０ 例正常人比较。结果： 结直肠癌患者红细胞免疫功能和 Ｔ 淋巴细胞免疫功能明显低于正常人（ Ｐ＜ ０００１） 。结论： 结直肠癌患者的红细胞免疫功能和 Ｔ淋巴细胞免疫功能明显障碍。临床上应重视免疫监测， 加强免疫支持治疗。
Objective: To study changes on immunologic function of erythrocyte and T lymphocyte subpopulation in patients with colorectal cancer. Method:The immunologic functions of 26 and 36 patients with colonic cancer and rectal cancer were determined, taking the rate of RBC C 3b receptor rosette(RCRR), RBC immune complex rosette(RICR),tumor RBC rosette(TRR) and CD + 3, CD + 4, CD + 8 cells as observation indexes, while compared with 30 normals. Result: The immunologic functions of erythrocyte and T lymphocyte subpopulation in patients with colorectal cancer were significantly lower than those of the controls(P<0 001). Conclusion: The immunologic functions of erythrocyte and T lymphocyte subpopulation in patients with colorectal cancer were obviously inhibited. It is clinically to take the immunologic monitoring seriously, strengthen immune and stand by the therapy.
出处
《汕头大学医学院学报》
1999年第2期27-28,共2页
Journal of Shantou University Medical College
