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乳铁蛋白生物学特性及其在断奶仔猪生产中的应用研究 被引量：2

Biological Functions of Lactoferrin and its application on the production of Weaning Piglets
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摘要 乳铁蛋白是一种存在于哺乳动物外分泌液中的非血红素铁结合性糖蛋白,它具有多种生物活性功能。本文主要就乳铁蛋白的生物学功能及其在仔猪中生产中的应用前景做一综述。 Lactoferrin is a glycoprotein of non-heme iron associativity,it exists in external secretions of mammalian.It has a variety of biological activity.This review focuses on the biological functions of lactoferrin and its application prospect of piglets in production
作者 张凯 方热军
机构地区 饲料安全与高效利用教育部工程研究中心
出处 《广东饲料》 2011年第1期24-26,共3页 Guangdong Feed
关键词 乳铁蛋白 生物活性 生产应用 Lactoferrin Biological activity Application Weaning piglets
分类号 S828.5 [农业科学—畜牧学]
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参考文献8

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  • 1Lonnerdal, B and S Iyer. Lactoferrin: molecular structure and biological function. Annu Rev Nutr, 1995,15:93-110.
  • 2Masson, P L and J F Heremans. Studies on lactoferrin, the iron binding protein of secretions. Prot Biol Fluids, 1966,14:115-124.
  • 3Metz-Boutigue, M H S. Human lactotransferrin: amino acid sequence and structural comparisons with other transferrins. Eur J Biochem, 1984,145:659-676.
  • 4Nibbering, P H , E Ravensbergen, M M Welling, L A van Berkel, P H van Berkel, E K Pauwels, and J H Nuijens. Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria. Infect Immun, 2001,69:1 469-1 476.
  • 5Nikawa, H , L P Samaranayake, J Tenovuo, and T Hamada. The effect of antifungal agents on the in vitro susceptibility of Candida albicans to apo-lactoferrin. Arch Oral Biol, 1994,39:921-923.
  • 6Rey, M W , S L. Woldshuk, H A de Boer, and F R Pieper. Complete nucleotide sequence of human mammary gland lactoferrin. Nucleic Acids Res, 1990, 18:5 288-5 288.
  • 7Anderson, B F , H M Baker, G E Norris, D W Rice, and E N Baker. Structure of human lactoferrin: Crystallographic structure analysis and refinement at 2.8 A resolution.J Mol Biol, 1989,209:711 -734.
  • 8Appelmelk B J.lactoferrin is a lipid a-binding protein [J].Infectionand Immunity, 1994,62:2 628-2 632.
  • 9Asanuma, H , K Numazaki, N Nagata, T Hotsubo, K Horino, and S Chiba. Role of milk whey in the transmission of human cytomegalovirus infection by breast milk. Microbiol Immunol,1996,40: 201 -204.
  • 10Baveye, S , E Elass, J Mazurier, and D Legrand. Lactoferrin inhibits the binding of lipopolysaccharides to L-sclectin and subsequent production of reactive oxygen species by neutrophils. FEBS Lett, 2000,469:5-8.

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广东饲料
2011年 第1期

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