药物保守治疗未破裂型输卵管妊娠的临床评价

目的探讨药物保守治疗未破裂型输卯管妊娠的临床疗效和安全性。方法将80例未破裂型输卯管妊娠患者随机分成观察组和对照组，各40例，观察组应用甲氨喋呤联合四氢叶酸钙，对照组应用大剂量米非司酮，观察两组患者的临床疗效、血B—HCG下降情况、腹痛消失时问及药物副反应。结果观察组治疗效果好于对照组（P〈0．05），如治愈率高于对照组、腹痛消失时间短于对照组。结论甲氨喋呤联合四氢叶酸钙保守治疗未破裂型输卯管妊娠的临床效果好、副反应小，有利于患者的身体健康。

Objective To explore the clinical effect and safety of drugs conservatively treating un - cracked oviduct pregnancy conservatively, and to find more appropriate drugs. Methods 80 patients with un - cracked oviduct pregnancy were randomly divided into the intervention group（40 cases） and control group （40 cases）. The intervention group were treated with methotrexate combined calcium folinate, the control group were treated with high dose mifepristone. To observe the clinical efficacy of two groups, the decline of the blood [3 - HCG,pain disappeared time and adverse drug reactions. Results To compare two sets of data, such as the total cure rate,pain disappeared time, et al, significant difference （ P 〈 0. 05 ）. Conclusion The methotrexate combined with calcium folinate conservatively treating un - cracked oviduct pregnancy has good clinical efficacy, fewer adverse drug reactions, and hence is woithy of being recommended in clinical practice.