期刊文献+

急性脑梗死继发性损害的影像学研究 被引量:2

下载PDF
导出
摘要 急性脑梗死(acute cerebral infarction,ACI)是缺血性卒中的总称,包括脑血栓形成、腔隙性梗死和脑栓塞等,约占全部脑卒中的70%,是临床上常见病、多发病,严重危害中、老年人的身体健康。ACI是脑血液供应障碍引起缺血、缺氧,导致局限性脑组织缺血性坏死或脑软化。急性ACI后中枢神经系统大部分神经元在其轴索或者胞体损伤后可出现萎缩,或者在与之相互联系的传出或传入神经元死亡后出现萎缩,前者即华勒变性(Wallerian Degeneration,WD),后一现象则称为经神经元变性或递质性神经元变性(transneuronealdegeneration),由于两者都是继发于原发病灶损伤后在远隔部位出现的病理生理改变或变性,故又常称作继发性损伤(SecondaryDamage)或继发性变性(Sec—ondaryDegeneration)。现就该领域的研究做一综述。
出处 《浙江临床医学》 2011年第2期216-217,共2页 Zhejiang Clinical Medical Journal
  • 相关文献

参考文献20

  • 1周艳霞,白润涛,韩漫夫,龙霞.脑梗塞后锥体束Wallerian变性的MRI表现[J].海南医学,2010,21(8):16-18. 被引量:3
  • 2Rovin A,Grive E,Rovira A,et al.Distribution terrtoies and causative mechanisms of ischemic stroke.Eur Radiol,2005,15(3):416-426.
  • 3梁志坚,刘斯润,曾进胜,凌雪英,徐安定,余剑,王芳,凌莉,侯清华,邢世会.局灶性脑梗死继发逆行性神经纤维变性及其临床意义[J].中国神经精神疾病杂志,2007,33(12):711-714. 被引量:13
  • 4Wang Z,Dai CF,Chi F.Retrograde degeneration of the facial nerve after acute traction on parotid gland an experimental investigation.Otolaryngol Head Neck Surg,2002,127(1):55-59.
  • 5Beirowski B,Adalbert R,Wagner D,et al.The progressive nature of Wallerian degeneration in wild type and slow Wallerian degeneration (WldS)nerves.BMC Neurosci,2005,6(1):6.
  • 6Zhi-Jian Liang,Jin-Sheng Zeng.Diffusion tensor imaging of secondary damage in remote areas after cerebral infarction.Cerebroavsc dis foreign Med Sci,2005,13(7):510-512.
  • 7Mazumdar A,Mukherjee P,Miller JH,et al.Diffusion-weighted imaging of acute cortico spinal tract injury preceding wallerian degeneration in the maturing human brain.AJNR Am J Neuroradiol,2003,24(6):1057-1066.
  • 8Francisco P,Joan M,Alex R,et al.Higher risk of further vascular events among transient ischemic attack patients with diffusion-weighted imaging acute ischemic lesions.Stroke,2004,35(10):2313-2319.
  • 9张勇,张焱.早期缺血性脑梗死磁共振扩散加权成像的实验研究[J].河南大学学报(医学科学版),2004,23(1):5-7. 被引量:4
  • 10殷信道,顾建平,王丽萍,卢铃铨,冯晓源.超急性脑梗死再灌注弥散加权——灌注磁共振成像实验研究[J].实用放射学杂志,2004,20(9):769-773. 被引量:8

二级参考文献67

  • 1姚桂兰,白树风.脑血管病引起的大脑脚萎缩[J].中国实用神经疾病杂志,1998,7(2):11-12. 被引量:1
  • 2Fiskum G, Murphy AN, Beal MF. Mitochondria in neurodegeneration: acute ischemia and chronic neurodegenerative diseases[J].J Cereb Blood Flow Metab,1999,19(4):351-369.
  • 3Guo J,Meng F,Zhang G,et al.Free radicals are involved in continuous activation of nonreceptor tyrosine protein kinase c-Src after ischemia/reperfusion in rat hippocampus[J].Neurosci Lett,2003,345(2):101-104.
  • 4Charriaut-Marlangue C, Margaill I, Represa A, et al. Apoptosis and necrosis after reversible focal ischemia: an in situ DNA fragmentation analysis[J].J Cereb Blood Flow Metab,1996,16(2):186-194.
  • 5Abe K, Aoki M, Kawagoe J, et al. Ischemic delayed neuronal death: a mitochondrial hypothesis[J].Stroke,1995,26(8):1478-1489.
  • 6van Dorsten FA, Hata R, Maeda K, et al. Diffusion-and perfusion -weighted imaging of transient focal cerebral ischemia in mice[J].NMR Biomed,1999,12(8):525-534.
  • 7Jiang Q,Zhang RL,Zhang ZG, et al. Magnetic resonance imaging indexes of the therapeutic efficacy of recombinant tissue plasminogen activator treatment of rat 1 and 4 hours after embolic stroke[J].J Cereb Blood Flow Metab,2000,20(1):21-27.
  • 8Sakoh M, Rohl L, Gyldensted C, et al. Cerebral blood flou and blood volume measured by magnetic resonance imaging bolus tracking after acute stroke in pigs: comparison with [15O]H2O positron emission tomography[J].Stroke,2000,31(8):1958-1964.
  • 9Li F, Silva MD, Sotak CH, et al. Temporal evolution of ischemic injury evaluated with diffusion-, perfusion- and T2-weighted MRI[J].Neurology,2000,54(3):689-696.
  • 10Li F, Han SS, Tatlisumak T, et al. Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal brain ischemia in rats[J].Ann Neurol,1999,46(3):333-342.

共引文献23

同被引文献22

引证文献2

二级引证文献2

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部