摘要
本文综述了近几年来国际上对纤维素堆囊菌分泌的天然抗癌化合物epothilones的研究进展。其中 ,简要介绍了 epothilones的由来、化学结构、合成方法 ,着重介绍了 epothilone与 Taxol在微管聚合特性上的性能比较。
The most recently progress of investigation for the novel natural anti cancer compound Epothilones,which is produced by Sorangium cellulosum (Myxobacteria),was summarized,including to briefly introduce their origin,chemical structures and synthesis practices,and to focus on the comparison of microtubule polymerization properties between Epothilones and Taxol.
出处
《天然产物研究与开发》
CAS
CSCD
1999年第3期77-81,共5页
Natural Product Research and Development
基金
国家自然科学基金资助
关键词
EPOTHILONE
粘菌
天然产物
微管蛋白
抗癌化合物
Epothilone,Taxol,Myxobacteria,Natural production,Microtubule protein,Polymerization,Anti cancer compound
