即食酵母粉对小鼠的免疫增强作用的研究

Research of Instant Yeast on Mice Immunity

目的评价即食酵母粉对小鼠的免疫增强作用。方法按人体摄入量10倍、20倍、30倍给小鼠灌胃30d,测小鼠胸腺/体重比值、细胞免疫功能、体液免疫功能、单核-巨噬细胞功能、NK细胞活性。结果20倍、30倍剂量组能显著提高小鼠胸腺/体重比值(P<0.05);20倍、30倍剂量组能显著增强淋巴细胞增殖能力(P<0.05),30倍剂量组能明显增强迟发型变态反应(P<0.05);30倍剂量组能明显增强小鼠的体液免疫功能、单核-巨噬细胞功能、小鼠NK细胞活性(P<0.05)。结论即食酵母粉对小鼠的免疫活性有显著的增强作用。

Objective：To evaluate the efficiency of instant yeast to improve mice immunity.Methods：Intake by the man 10,20,30times continuously fed to mice for 30 days,measured thymus/body weight ratio,cellular immunity,humoral immunity,monocyte-macrophage function,NK cell activity.Results：The 20,30 times dosage groups could significantly increase the thymus/body weight ratio（P〈0.05）;the 20,30 times dose can significantly enhance the ability of lymphocyte proliferation（P〈0.05）,the 30 times dose could significantly enhance DTH（P〈0.05）;the 30 times dose could significantly enhance the humrol immune function,monocytes-macrophages function,NK cell activity in mice（P〈0.05）.Conclusion：Instant yeast showed the effect to enhance the immunity of mice.