弥漫性肺间质疾病中医证素分布规律的临床文献研究

Literature study on TCM syndrome dlements distribution law of diffuse interstitial lung disease

目的:探讨弥漫性肺间质疾病中医证素分布规律。方法:从中国生物医学文献数据库、中国学术期刊全文数据库和中国中医药文献检索系统数据库,检索近15年弥漫性肺间质疾病文献,筛选整理规范名称,对病性证素与病位证素的分布组合规律进行分析。结果:弥漫性肺间质疾病的病性证素以气虚、血瘀、阴虚和痰为主;病位证素以肺和肾为主。单一病性证素与病位证素组合时,肺气虚最常见;二病性证素组合时,气虚血瘀最为常见,病位多在肺肾;三病性证素组合时,气阴两虚兼血瘀及痰瘀互阻兼气虚较为常见,主要病位在肺肾。四病性证素组合时以气阴两虚、痰瘀互阻较为常见,病位在肺肾。结论:弥漫性肺间质疾病的病位主要在肺肾,病性主要为气虚、血瘀、阴虚和痰,为进一步开展病机及诊断标准的制定提供依据。

Objective： To probe distribution regularity of TCM syndromes of diffuse interstitial lung disease.Methods： Literatures about diffuse interstitial lung disease in 15 years were collected from the Chinese biological medicine on disc,China national knowledge infrastructure and TCM database.The name of the disease was filtered.The distribution and association law of the nature and location pattern elements were analyzed.Results： Deficiency of vital energy,blood stasis,yin-deficiency and phlegm were the main nature elements of pattern of diffuse interstitial lung disease.Lung and kidney were the main location elements of pattern.In combination with single nature element and location element,the deficiency of lung qi was the most common one;in combination with two nature element the deficiency of vital energy and blood stasis the most common one,the location elements of pattern were the lung and kidney;in combination of three nature elements,the qi and yin deficiency with blood stasis and phlegm and blood stasis with qi deficiency was the more common one,the mainly location elements of pattern were the lung and kidney;in combination of four nature elements,the qi and yin deficiency and the phlegm and blood stasis were the more common one,the location element were lung and kidney.Conclusion： Lung and kidney were the main locations of the disease,while deficiency of vital energy,blood stasis,yin-deficiency and phlegm were the main nature of disease,can providing the scientific basis for study of pathogenesis and the establishing of standardization of TCM syndrome.