小儿单纯糠疹与血微量元素之间关系探讨

Study of relationships between pityriasis simplex in children and their blood trace elements

目的对小儿单纯糠疹发病原因与微量元素之间的关系进行研究,找出二者之间的联系。方法收集上海市儿童医院皮肤科门诊2009年3月至2010年3月单纯糠疹病例340例,及同期该院儿保门诊健康体检儿童220例,均作血清微量元素（包括铜、钙、镁、铁、铅、镉、锌）检测,对两组数据进行统计学分析。结果单纯糠疹患儿组血锌水平均值（53.8~73.3μmol/L）显著低于健康对照组（75.7~97.6μmol/L）,其差异有统计学意义（P〈0.05）;血铜、钙、镁、铁、铅、镉水平与健康对照组比较差异无统计学意义（P〉0.05）。结论小儿单纯糠疹发病与锌元素缺乏关系密切。

Objective To discuss the relationships between the causes of pityriasis simplex in children and their blood trace elements.Methods To collect clinical and laboratory materials of 340 cases of pityriasis simplex in our hospital from March 2009 to March 2010.All of these patients received the study of blood trace elements including copper,calcium,magnesium,lead,iron,cadmium and zinc.The relationships between clinical information and outcomes of laboratory study were analyzed.Results The blood level of zinc in children with pityriasis simplex（53.8-82.4 μmol/L）was obviously lower than that of the normal control group（75.8~97.4 μmol/L） with statistical difference（P0.05）;The other blood trace elements including copper,calcium,magnesium,lead,iron,cadmium showed no statistical difference between the healthy control group and the sick group.Conclusion Children with lack of trace element zinc are prone to develop pityriasis simplex.